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. 2012 May 16;7(5):e37303. doi: 10.1371/journal.pone.0037303

Figure 2. A genetic screen for Eph pathway signaling molecules.

Figure 2

A) The wild-type adult eye displays a regular ommatidial lattice. B) The rough-eye phenotype generated by expression of UAS-ephrin under control of the sevenless2-GAL4 driver (SE) used to screen for modifier mutations. C) Near-complete suppression of the SE phenotype by co-expression of a dominant-negative eph transgene (ephDN). D) Suppression of the SE phenotype by the reph1 allele. E) Suppression of the SE phenotype by rephk8617. F) Co-expression of a UAS-reph+ transgene enhances the SE phenotype. All images (20×) were acquired through a digital camera attached to a Zeiss Stemi SV11 stereo dissecting microscope. Images were captured using FPG3 software.