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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Am J Surg Pathol. 2012 Jun;36(6):876–882. doi: 10.1097/PAS.0b013e31824e133f

Table 3.

BRAF mutation according to polyp subtype and location.

Polyp subtype BRAF, n (%) P value, proximal vs. distal
Proximal Distal Overall*
Tubular adenoma 1/12 (8) 0/10 (0) 1/32 (3) 1
Tubulovillous adenoma 0/0 (0) 0/4 (0) 0/9 (0) NA
Microvesicular hyperplastic polyp 27/36 (75) 42/53 (79) 80/105 (76) 0.64
Goblet cell hyperplastic polyp 0/5 (0) 0/12 (0) 0/20 (0) NA
Sessile serrated adenoma/polyp 32/35 (91) 10/15 (67) 60/71 (85) 0.029
Sessile serrated adenoma/polyp with dysplasia 9/10 (90) 8/8 (100) 19/20 (95) 1
Traditional serrated adenoma 5/10 (50) 1/2 (50) 7/13 (54) 1
*

The overall number for each polyp subtype also comprises polyps with unknown location;

NA: not assessable.