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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Curr Pharm Biotechnol. 2012 May 1;13(6):819–826. doi: 10.2174/138920112800399284

Figure 2.

Figure 2

Effect of carbon monoxide releasing molecules (CORMs), CORM-3, and CORM-A1 on mortality and plasma creatinine in C57BL/6J mice treated with cisplatin. A) Kaplan–Meier survival curve of mice after injection of cisplatin (CP) and subsequent treatment with vehicle, CORM-3, inactive CORM-3 (iCORM-3), and CORM-A1 (n=8). Treatment with CORM-3 and CORM-A1 increased the survival rate as compared to untrated (CP) and iCORM-3 treated mice. B) Plasma creatinine levels in mice following CP treatment. Treatment with CORM-3 and CORM-A1 significantly blunted the increase in plasma creatinine as compared to CP treated mice, n=8. *= statistically significant P< 0.05 as compared to CP treated mice.