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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Nanomedicine. 2012 Feb 1;8(7):1043–1051. doi: 10.1016/j.nano.2012.01.005

Figure 1.

Figure 1

(a) Schematic illustration of QD conjugates for biomarker targeting: (QD-L-PEG) CdSe/(Cd,Zn)S QDs with 80 mol% MHPC and 20 mol% DPE-Peg 2k. (QD-L-COOH) QDs with 80 mol% MHPC, 15 mol% DPE-PEG2k, and 5 mol% DPE-PEG2k-COOH. (QD-L-Ab) QD-L-COOH covalently conjugated with an average of three targeting antibodies per QD. (b) Particle size distributions for QD conjugates. (c) Zeta potential for QD conjugates. A zeta potential of about −10 mV minimizes aggregation and non-specific binding. (d) Absorbance and emission spectra for QD-L-PEG (Em. 623 nm) in water. (e) Quantum yield for QD conjugates in water.