Figure 7.

Quantification of starved insulin signaling pathway mutant ovary phenotypes. Insulin mutants were deprived of amino acids similar to WT starved flies. Bar graphs shows the percentage of degenerating egg chambers compared with Pwops in well-fed versus starved flies. WT, InR³³⁹ GLC, chico¹/Df, Akt^q GLC, Tor^ΔP GLC, and S6k^l−1 GLC comparison of well fed versus starved had a P-value >0.05 indicating there was no significant difference, whereas chico¹ GLCs had a P-value <0.05. (WT P-value=1, InR³³⁹ GLCs P-value=0.064, chico¹ GLCs P-value=0.039, chico¹/Df P-value=0.6234, Akt^q GLCs P-value=0.308, Tor^ΔP GLCs P-value=0.1471, and S6k^l−1 GLCs P-value=1). The total numbers of egg chambers (degenerating+Pwop) for starved flies were: 54 (WT), 192 (InR³³⁹ GLCs), 61 (Akt^q GLCs), 47 (chico¹ GLCs), 49 (chico¹ /Df), 55 (Tor^ΔP GLCs), 46 (S6k^l−1 GLCs). Data for the well-fed flies were the same as in Figure 1 or Supplementary Figure 1. Error bars represent S.E. calculated using a standard two-tailed t-test