Table 3.
Comparison of comprehensive metabolic panel results from phase I and II
| Phase I | Phase II | Reference values | ||||
|---|---|---|---|---|---|---|
| Baseline N = 9 | 3 Weeks N = 9 | Baseline N = 5 | 3 Weeks N = 5 | 3 Months N = 5 | ||
| Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | ||
| Glucose (mg dL−1) | 87 ± 4 | 91 ± 6a | 87 ± 5 | 91 ± 5 | 96 ± 6b | 65–99 mg dL−1 |
| Blood urea nitrogen (BUN) (mg dL−1) | 11 ± 1 | 12 ± 1 | 11 ± 1 | 12 ± 2 | 10 ± 1 | 5–26 mg dL−1 |
| Creatinine (mg dL−1) | 0.9 ± 0.0 | 0.9 ± 0.5 | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.8 ± 0.1 | 0.5–1.5 mg dL−1 |
| BUN/creatinine ratio | 12 ± 1 | 14 ± 1 | 12 ± 2 | 14 ± 2 | 12 ± 2 | 8–27 |
| Sodium (mmol L−1) | 139 ± 0.4 | 139 ± 1 | 139 ± 1 | 139 ± 1 | 140 ± 1 | 135–148 mmol L−1 |
| Potassium (mmol L−1) | 3.9 ± 0.1 | 4.3 ± 0.1 | 3.9 ± 0.1 | 4.3 ± 0.1 | 4.0 ± 0.1 | 3.5–5.5 mmol/L |
| Chloride (mmol L−1) | 105 ± 1 | 103 ± 1 | 105 ± 1 | 103 ± 1 | 103 ± 1 | 96–109 mmol L−1 |
| Carbon dioxide, total (mmol L−1) | 24 ± 1 | 24 ± 1 | 24 ± 2 | 24 ± 1 | 24 ± 1 | 20–32 mmol L−1 |
| Calcium (mg dL−1) | 9.4 ± 0.2 | 9.4 ± 0.1 | 9.4 ± 0.3 | 9.4 ± 0.1 | 9.4 ± 0.2 | 8.5–10.6 mg dL−1 |
| Protein, total (g dL−1) | 8.5 ± 0.3 | 8.4 ± 0.3 | 8.5 ± 0.3 | 8.4 ± 0.2 | 8.3 ± 0.3 | 6.0–8.5 g dL−1 |
| Albumin (g dL−1) | 4.0 ± 0.1 | 4.0 ± 0.1 | 4.0 ± 0.1 | 4.0 ± 0.1 | 3.9 ± 0.1 | 3.5–5.5 g dL−1 |
| Globulin(g dL−1) | 4.4 ± 0.4 | 4.4 ± 0.3 | 4.4 ± 0.3 | 4.4 ± 0.3 | 4.4 ± 0.3 | 1.5–4.5 g dL−1 |
| A/G ratio | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.9–2.5 |
| Bilirubin, total (mg dL−1) | 0.3 ± 0.0 | 0.4 ± 0.1 | 0.3 ± 0 | 0.4 ± 0.1 | 0.4 ± 0.0 | 0.1–1.2 mg dL−1 |
| ALP (IU L−1) | 85 ± 12 | 82 ± 18 | 85 ± 4 | 82 ± 6 | 89 ± 6 | 25–150 IU L−1 |
| AST (IU L−1) | 29 ± 4 | 29 ± 3 | 29 ± 4 | 29 ± 3 | 29 ± 4 | 0–40 IU L−1 |
| ALT (IU L−1) | 24 ± 5 | 25 ± 5 | 24 ± 5 | 25 ± 6 | 26 ± 9 | 0–40 IU L−1 |
Mean ± SE mean ± standard error, BUN blood urea nitrogen, ALP alkaline phosphatase, AST aspartate transaminase, ALT alanine transaminase
aOne subject excluded because not fasting; n = 8
bOne subject excluded because not fasting; n = 4