Table 3.

The comparison (Fisher' Exact Test) of the frequency of adverse events in two groups (%).

	Donepezil	Donepezil plus Hirudin	P values
Total adverse events	30 (71.4)	38(90.5)	0.17
Hypersensitiveness	1 (2.4)	3 (7.1)	0.24
Hemorrhage	1 (2.4)	5 (11.9)	0.08
Bradycardia	2 (4.8)	1 (2.4)	0.56
Anorexia	2 (4.8)	2 (4.8)	1.00
Hypertension	2 (4.8)	2 (4.8)	0.64
Infection	3 (7.1)	3 (7.1)	0.67
Abnormal dreams	2 (4.8)	2 (4.8)	0.64
Headache	2 (4.8)	3 (7.1)	1.00
Vomiting	3 (7.1)	3 (7.1)	0.67
Accidental injury	3 (7.1)	4 (9.5)	1.00
Nausea	4 (9.5)	4 (9.5)	0.70
Diarrhea	5 (11.9)	6 (14.3)	1.00