Table 1.

Summary of gene set enrichment analysis (GSEA) results for the colorectal cancer (CRC) related microarray – GSE8671, based on the 73 gene sets searched from MSigDB by using query term – “colon.”

Enrichment	Normal vs. cancer	Cancer vs. normal
Up-regulated	22 Gene sets	29 Gene sets
Significant at FDR <25%	8 Gene sets	14 Gene sets
Nominal p-value <5%	7 Gene sets	12 Gene sets
Nominal p-value <1%	5 Gene sets	6 Gene set

If the number of genes in a gene set falls below the threshold value of 15 in GSEA, we simply filled these gene sets out. FDR, false detection rate.