Table 1.
ALCAR does not affect the cytotoxic potential of paclitaxel
| OVCAR-3 cells | Luminescence | SD | Range
|
p-value | |
|---|---|---|---|---|---|
| Min | Max | ||||
| ALCAR | |||||
| 0 μM | 30,700 | ±2965 | 27,410 | 34,210 | Control |
| 1 μM | 26,320 | ±2238 | 23,550 | 28,430 | <.05 |
| 10 μM | 32,950 | ±1085 | 31,670 | 34,230 | >.05 |
| 100 μM | 36,050 | ±1930 | 33,930 | 38,490 | <.05 |
| ALCAR and Paclitaxel | |||||
| 0 μM | 12,720 | ±352 | 12,380 | 13,210 | Control |
| 1 μM | 13,540 | ±811 | 12,390 | 14,300 | NA |
| 10 μM | 13,950 | ±1330 | 12,320 | 15,190 | NA |
| 100 μM | 12,960 | ±462 | 12,400 | 13,420 | NA |
| SKOV-3 cells
| |||||
| ALCAR | |||||
| 0 μM | 24,070 | ±2631 | 20,590 | 26,220 | Control |
| 1 μM | 23,570 | ±2347 | 21,110 | 25,870 | >.05 |
| 10 μM | 27,400 | ±590.1 | 26,570 | 27,910 | >.05 |
| 100 μM | 30,660 | ±894.3 | 29,910 | 31,920 | <.01 |
| ALCAR and Paclitaxel | |||||
| 0 μM | 15,240 | ±486.1 | 14,640 | 15,700 | Control |
| 1 μM | 15,370 | ±611.9 | 14,800 | 15,910 | NA |
| 10 μM | 15,320 | ±1090 | 13,770 | 16,340 | NA |
| 100 μM | 14,440 | ±1052 | 13,720 | 15,980 | NA |
SD—standard deviation; Min—minimum value; Max—maximum value; NA—not available {ANOVA indicated no significant difference}.