Table 2.
Baseline characteristics of subjects who showed an upward shift in FEV1/FVC category between their baseline and final visits
| Subgroup | ||||||
|---|---|---|---|---|---|---|
| D (n = 177) | E (n = 64) | F (n = 289) | ||||
| LLN + Fixed + → LLN-Fixed+ | LLN + Fixed + → LLN-Fixed- | LLN-Fixed + → LLN-Fixed- | ||||
|
Non-smokers (n = 97) |
Smokers (n = 80) |
Non-smokers (n = 33) |
Smokers (n = 31) |
Non-smokers (n = 210) |
Smokers (n = 79) |
|
| Males, n (%) | 65 (67) | 44 (55) | 16 (49) | 8 (26) | 105 (50) | 42 (53) |
| Age, years (SD) | 63.4 (10.3) | 58.9 (10.0) | 53.7 (11.2) | 52.7 (7.7) | 63.4 (9.7) | 60 (10.6) |
| Baseline postbronchodilator FEV1/FVC (SD) | 0.56 (0.06) | 0.57 (0.06) | 0.61 (0.06) | 0.60 (0.06) | 0.67(0.03) | 0.67 (.02) |
| Baseline postbronchodilator FEV1, liters (SD) | 1.86 (0.59) | 1.99 (0.65) | 2.08 (0.65) | 1.87 (0.59) | 2.26 (0.71) | 2.24 (0.62) |
| as % predicted* (SD) | 59.7 (13.2) | 61.7 (14.0) | 64.3 (15.4) | 63.5 (14.0) | 74.8. (12.2) | 71.1 (11.3) |
* based on Swanney prediction equations [6]