Table 1. Somatic cancer mutations of LGR6 listed in the COSMIC database as of Jan-2012.

Cancer	Mutation	Affected Domain	Zygosity	Mutated/Total Cases (%)
Colon (adenocarcinoma)	P928H	C-terminal tail	Homozygous	3/37 (8%)
	G725C	Extracellular loop 2	Heterozygous
	S299insGRS	ECD	Heterozygous
Pancreas	V746I	TM5	Heterozygous	1/23 (4%)
Ovary (serous carcinoma)	F230fs*6	ECD	Heterozygous	2/3 (67%)
	D536G	ECD	Heterozygous