Table 1. Main characteristics of all studies included in the meta-analysis.
| Author, year | Country | Ethnicity | Cancer type | Gene type | Genotyping method | No. (cases/controls) | Case(%) | contrlo(%) | ||||
| AA | AG | GG | AA | AG | GG | |||||||
| Park 2006 [5] | Korea | Asian | Lung | rs4645978 | PCR-RFLP | 432/432 | 148(34.3) | 225(52.0) | 59(13.7) | 138(32.0) | 215(50.0) | 79(18.0) |
| Gangwar 2009 [17] | India | Caucasian | Bladder | rs4645978 | PCR-RFLP | 212/250 | 81(38.2) | 103(49.0) | 28(13.2) | 89(36.0) | 99(40.0) | 62(25.0) |
| Theodoropoulos 2010 [14] | Greece | Caucasian | Pancreatic | rs4645978 | PCR-RFLP | 80/160 | 305(50.2) | 3(3.75) | 46(57.5) | 36(23.0) | 91(57.0) | 33(21.0) |
| Kesarwani 2010 [15] | India | Caucasian | Prostate | rs4645978 | PCR-RFLP | 173/198 | 82(47.4) | 42(24.0) | 49(28.3) | 70(35.0) | 81(41.0) | 47(24.0) |
| Lee 2010 [7] | Korea | Asian | Lung | rs4645978 | PCR-RFLP | 720/720 | 260(36.1) | 349(49.0) | 111(15.4) | 269(37.0) | 325(45.0) | 126(18.0) |
| Liamarkopoulos2011 [10] | Greece | Caucasian | Gastric | rs4645978 | PCR-RFLP | 88/480 | 44(50.0) | 34(39.0) | 10(11.4) | 116(24.0) | 239(50.0) | 125(26.0) |
| Theodoropoulos 2011 [12] | Greece | Caucasian | Colorectal | rs4645978 | PCR-RFLP | 402/480 | 155(38.6) | 181(45.0) | 66(16.5) | 116(24.0) | 239(50.0) | 125(26.0) |
| George 2011 [16] | India | Caucasion | Prostate | rs4645978 | PCR-RFLP | 165/205 | 77(46.3) | 40(24.0) | 48(29.3) | 77(46.3) | 40(24.0) | 48(29.3) |
| Wang 2011 [18] | China | Asian | Thyroid | rs4645978 | PCR-RFLP | 118/213 | 41(34.7) | 62(53) | 15(12.8) | 69(32.4) | 93(43.7) | 51(23.9) |