Table 1. Clinical characteristics of control and Type 2 diabetic nephropathy patients.
| Clinical Characteristic | Control (n = 12) | Diabetic Nephropathy (n = 15) | P value |
| Age (years) | 56 (52;60) | 56 (51.9;63.5) | 0.83 |
| Male sex (%) | 75% | 66% | 0.67 |
| Urine protein-to-creatinine ratio (g/g) | –* | 5.3 (3.9;7.8) | – |
| Blood urea nitrogen (mg/dL) | 15 (12.8;17.3) | 51 (39.5;63.3) | <0.0001 |
| Serum creatinine (mg/dl) | 1.0 (0.8;1.1) | 4.1 (2.7;4.8) | 0.0005 |
| estimated GFR (ml/min/1.73 m2) | 86.8 (61.8;103.7) | 13.35 (12.5;40.7) | 0.0008 |
| Serum albumin (g/dl) | 4.2 (3.7;4.4) | 2.5 (2.3;3.6) | 0.0002 |
| Systolic blood pressure mm/Hg | 127 (120;130) | 150 (140;166) | 0.0002 |
| Diastolic blood pressure (mm/Hg) | 80.5 (73.4;86.2) | 85 (76;91) | 0.49 |
| HbA1C% | 6.5 (4.5;10.9) | 9.3 (7.8;11.8) | 0.10 |
| ACEI† (%) | 25% | 73% | 0.026 |
| ARB‡ (%) | 8.3% | 26% | 0.25 |
Data are presented as median (interquartile range) for continuous variables and % for categorical variables.
*
Urine protein-creatinine ratio not available for control patients as their urinalyses did not show proteinuria.
†
ACEI: angiotensin converting enzyme inhibitors.
‡
ARB: angiotensin receptor blockers.