Table 2. Association Results for Seven Index SNPs Representing Independent Loci.

SNP	Position	Minor allele	Minor allele freq.	P-value	Odds ratio (95% C.I.)	No. Secondary SNPs	Multiple LR P-value No HRA Adj.#	Multiple LR P-value HRA Adj	Functional Genes*
rs9357152	32664960	G	0.12	7.28×10−24	0.24 (0.21–0.28)	34	0.0004	0.00012	HLA-DQB1
rs204991	32161366	G	0.46	1.13×10−12	2.24 (2.00–2.51)	33	3.31×10−9	0.0024	GPSM3
rs2523674	31436789	A	0.35	6.55×10−10	0.57 (0.52–0.62)	33	0.0014	0.00693	HCP5
rs2517485	31074101	A	0.49	2.03×10−9	1.77 (1.61–1.95)	35	6.53×10−5	0.0022	SEEK1/PSORS1C1
rs2260000	31593476	G	0.22	5.90×10−8	0.60 (0.54–0.66)	15	0.23	0.39	BAT2
rs9276435	32713867	A	0.40	3.28×10−7	1.82 (1.62–2.05)	5	0.00014	0.10	HLA-DQA2
rs2844776	30171827	G	0.37	4.17×10−7	1.65 (1.50–1.83)	4	0.052	0.096	TRIM26

^*Either the gene that the SNP occurs in, or the nearest gene within the same LD haplotype block as the index SNP.

^#Indicates adjustment for known common high-risk alleles by inclusion of the five-level variable computed by recursive partitioning.