Table 3.
Genes involved in apoptosis that decrease by at least 2 fold after PGRMC1 siRNA treatment of hGL5 cells
Gene Name | Fold Change | Gene Description | Putative Effect on Apoptosis |
---|---|---|---|
ITGB3BP | 2.73 | Integrin beta 3 binding protein (beta3-endonexin) | ↑ [35] |
NME5 | 2.53 | Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) | ↓ [36] |
LTA | 2.24 | Lymphotoxin alpha (TNF superfamily, member 1; TNF-beta) | ↑ [37] |
PPP2R1B | 2.23 | Protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform, transcript variant 2 | ↑ [38] |
ABL1 | 2.20 | v-abl Abelson murine leukemia viral oncogene homolog 1, transcript variant b | ↑ [39] |
GADD45G | 2.04 | Growth arrest and DNA-damage-inducible, gamma | ↑ [40] |