Table 1. Allele frequency and OR of the simulated common frequency (MAF ≥0.05) and low-frequency (MAF <0.05) causal variants per population.
Common variant allele frequency | OR | Rare variant allele frequency | OR | |
---|---|---|---|---|
Population 1 | 0.30 | 1.10 | 0.04 | 2.0 |
Population 2 | 0.15 | 1.15 | 0.01 | 2.0 |
0.20 | 1.15 | 0.01 | 2.5 | |
Population 3 | 0.40 | 1.10 | 0.02 | 2.0 |
0.15 | 1.20 | 0.01 | 3.0 |
Abbreviations: MAF, minor allele frequency; OR, odds ratio.