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. 2012 Feb 1;20(6):709–712. doi: 10.1038/ejhg.2011.274

Table 2. Single-point meta-analysis results summary.

Meta-analysis type Power (%) False-positive rate (%) 1 Causal variant found 2 Causal variants found 3 Causal variants found 4 Causal variants found 5 Causal variants found
MAF ≥0.05
P-value based 15.71 14.41 12.49 2.54 0.59 0.10 0
 OR based (fixed effects) 11.02 15.51 7.02 2.93 0.88 0.20 0
 OR based (random effects) 5.46 10.05 3.71 1.46 0.29 0 0
               
MAF <0.05
P-value based 100 71.97 19.26 42.65 30.78 6.96 0.34
 OR based (fixed effects) 98.28 51.76 57.95 31.99 7.14 1.20 0
 OR based (random effects) 6.45 13.93 5.76 0.69 0 0 0

Abbreviations: MAF, minor allele frequency; OR, odds ratio.