FIG. 3.
Effects of BFR exposure on the hepatic activities of drug-metabolizing enzymes. The activities of ethoxy-(EROD) (A), methoxy-(MROD) (B), propyloxy-(PROD) (C), and benzyloxy-(BROD) (D)-resorufin-O-deethylation were measured in hepatic S9 fractions prepared from frozen liver tissues, as described in the text. Activities were corrected for S9 protein levels and are expressed as mean ± SEM (n = 9–10 per group). *p < 0.05 compared with control.