FIG. 4.

BAL infiltrates after short-term exposure to 4-OPA. Analysis of percent neutrophils (A), eosinophils (B), and alveolar macrophages (C) after exposure to 4-OPA. Mice received 4 days of dermal exposure (concentration indicated on graph) followed by a pulmonary challenges of 4-OPA (1%). Aspiration controls (no dermal exposure) were also included on the graphs. Bars represent means ± SE of 7 mice per group. Levels of statistical significance are denoted as *p ≤ 0.05 and **p ≤ 0.01 as compared with vehicle control (no dermal or pulmonary exposure to 4-OPA).