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. Author manuscript; available in PMC: 2013 Jun 25.
Published in final edited form as: Physiol Behav. 2012 Mar 26;106(4):476–484. doi: 10.1016/j.physbeh.2012.03.019

Figure 1.

Figure 1

Effect of isolation versus pairing of female prairie voles on contractile responses of their aortic tissues to acetylcholine (ACh). *Isolation significantly enhanced ACh-induced contractions in aortic tissues with endothelium intact (left), as determined by a significant factor interaction effect from mixed-design 2-factor ANOVA in which factor 1 (independent factor) = isolated or paired animal group and factor 2 (repeated measures factor) = ACh concentrations [F (7,224) = 2.10, p=0.04]. Removal of the endothelium (right) abolished the enhancing effect of isolation without significantly altering ACh contractions in aortic tissues from paired animals. Note: values are shown as mean ± SEM.