Table 3.
Antimalarial Activity of QN254 in the P. berghei Murine Modela
Dosing Regimen | Parasitemia Reduction (%) | Average Survival (days) | Cure Rate (%) | Toxicity Rate (%) |
---|---|---|---|---|
3 x 30 | > 99.99 | 28.4 | 80 | 0 |
3 x 60 | > 99.99 | Not available | 60 | 40b |
3 x 100 | > 99.99 | Not available | 20 | 80b |
Percent inhibition of parasitemia compared to untreated controls. The mean survival of control animals was 5.6 to 6.2 days
Mice died around day 10 and were parasite free.