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. 2012 Mar;12(5):473–483. doi: 10.2174/156802612799362977

Table 3.

Antimalarial Activity of QN254 in the P. berghei Murine Modela

Dosing Regimen Parasitemia Reduction (%) Average Survival (days) Cure Rate (%) Toxicity Rate (%)
3 x 30 > 99.99 28.4 80 0
3 x 60 > 99.99 Not available 60 40b
3 x 100 > 99.99 Not available 20 80b
a

Percent inhibition of parasitemia compared to untreated controls. The mean survival of control animals was 5.6 to 6.2 days

b

Mice died around day 10 and were parasite free.