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. 2012 Mar 28;12(4):4311–4323. doi: 10.3390/s120404311

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© 2012 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 2. — Comparison of the chromogenic assay with the optical biosensor based assay formats for a selection of small molecule and protein inhibitors. IC₅₀ values for the chromogenic assay are in μM, for the DBA in (A) and (B) K_d values are given in μM, for the substrate degradation assay (C) and the ISA (D), IC₅₀ values are given in μM. The solid lines show a 1:1 correlation.