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. 2012 May 1;4(3):326–340. doi: 10.4161/mabs.19941

graphic file with name mabs-4-326-g7.jpg

Figure 7. (A) Mean EC50 value and(B) Mean Relative ADCC activity of select AbX AF-blend samples with effector cells carrying different FcγRIIIa genotypes (VV: homozygous V158; VF: heterozygous with both V158 and F158; FF: homozygous F158). Relative ADCC activity was calculated by inverse normalization of EC50 values of samples with EC50 value of the sample containing 0% afucosylated material. Data presented are mean values from at least five in vitro ADCC experiments using different donors; error bars indicate corresponding standard deviations.