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The β-isoform of the catalytic A subunit (CnAβ) isoform is expressed in pancreatic acinar cells, and CnAβ-deficient mice have reduced pancreatic and acinar cell Cn phosphatase activity. A: DNA gel of PCR from acinar cell cDNA using Cn isoform-specific primers. B: Cn phosphatase activity from whole pancreas, acinar cells, and splenic lymphocytes. #P < 0.01 with respect to wild-type (WT). Data are means ± SE.
