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. 2012 May 1;3:81. doi: 10.3389/fpls.2012.00081

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Copyright © 2012 Wachter, Rühl and Stauffer.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.

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Arginine methylation and alternative splicing are linked in Arabidopsis. The arginine methyltransferase PRMT5 modifies both histone and non-histone targets, including the splicing factors GRP7 and GRP8 (Deng et al., 2010). Changes in alternative splicing (AS) affect diverse biological processes, such as FLK/FLC-mediated flowering control (Deng et al., 2010) and regulation of circadian rhythms via PRR9 (Sanchez et al., 2010). A connection between histone modifications and AS has been demonstrated in mammals (Luco et al., 2010), but so far not in plants.