Figure 2.

SL-1 induces a unique transcriptional signature in human leukocytes. The transcript profiles of hiDCs stimulated with P3K, SL-1, SL-A, or vehicle only were assessed by microarray. The 50 most highly upregulated and statistically significant transcripts (p < 0.02) induced by SL-1, SL-A, or P3K as compared to vehicle only treated cells were organized according to function. Due to limited overlap in genes upregulated by each stimulus, different functional categories were chosen. The percent overlap of gene identities between P3K vs SL-1, P3K vs SL-A, and SL-1 vs SL-A is highlighted. The identities of individual genes are listed in Supplementary Table 1.