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. 2012 Feb 24;7(5):863–870. doi: 10.1021/cb200311s

Table 1. Δstf0 Does Not Exhibit Global Defects in Cell Wall Integritya.

    WT Δstf0 Δstf0 + pstf0
detergents (% w/v) SDS 0.02 0.02 0.02
  DOC 0.010 0.007 0.008
antibiotics (μg/mL) rifampicin 0.025 0.0125 0.0125
  isoniazid 0.025 0.027 0.030
  amikacin 0.30 0.30 0.40
  kanamycin 1.1 1.5 >7.5b
a

Mtb was grown in the presence of each detergent or antibiotic. The minimal inhibitory concentration that inhibited 50% of Mtb growth was noted after 7 days. These data are representative of at least two independent experiments each performed in duplicate.

b

Δstf0 + pstf0 contains a kanamycin resistance gene.