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. 2012 Mar 11;22(7):930–938. doi: 10.1093/glycob/cws061

Fig. 4.

Fig. 4.

Relative quantitative analysis of the bone marrow samples in healthy donors and AML patients. With LacCer (1010) as the internal standard, relative quantity was represented by the ratios of abundance of Gb3, Lc3 and GM3 to LacCer. (A) Relative quantification of Gb3 (1214) in the bone marrow samples of healthy donors and AML patients. (B) Relative quantification of Lc3 (1255) in the bone marrow samples of healthy donors and AML patients. (C) Relative quantification of GM3 (1371) in the bone marrow samples of healthy donors and AML patients. (D) Relative quantification of nLc4 (1460) in the bone marrow samples of healthy donors and AML patients. The ratios of m/z 996 abundance to m/z 912 in the MS2 spectrum of m/z 1460 were chosen to represent the relative proportion of nLc4 (1460) in the mixture. Data represent the bone marrow samples from healthy donors (n = 16) and AML patients (n = 92). Statistical significance of differences between AML patients and controls was analyzed using the two-tailed Student's t-test of means. Compared with control, *P < 0.05, ***P < 0.001.