Table 3.

CD4⁺ T-cell subsets in primary immunodeficiencies

PID	CD4+ T cells	Naive CD4+ T cells	Memory CD4+ T cells	CXCR5+CD45RA+ CD4+ T cells	CXCR5+CD45RA− CD4+ T cells
IL12RB1 (n = 6)	40 ± 4.4	71 ± 4.7	28 ± 4.7	1.6 ± 0.46	14 ± 2.8
STAT1 (n = 6)	40*	41 ± 10	56 ± 10	3.9 ± 0.68	11 ± 2.3
STAT3 (n = 14)	41 ± 3.1	65 ± 3.8	33 ± 3.7	1.5 ± 0.29 (n = 11)	8.7 ± 1.6 (n = 11)
TYK2 (n = 2)	41*	53 ± 24	43 ± 27	2.8 ± 1.2	15 ± 5.4
Controls	43 ± 1.4 (n = 54)	39 ± 1.7 (n = 70)	59 ± 1.7 (n = 70)	2.8 ± 0.24 (n = 61)	15 ± 1.1 (n = 61)

Values are mean ± SEM percentage.

PID indicates primary immunodeficiency.

^*Analysis was only performed on 1 patient.