Table 1.

Cul2-type ubiquitin ligases and corresponding substrates.

Ubiquitin ligase	Substrates	References
pVHL	HIFα	Ivan et al. (2001); Jaakkola et al. (2001); Masson et al. (2001); Hon et al. (2002)
	Spry2	Anderson et al. (2011)
	EGFR	Zhou and Yang (2011)
	Atypical PKC (PKCλ and ζII)	Okuda et al. (2001); Iturrioz and Parker (2007)
	RPB7	Na et al. (2003)
	Rpb1	Kuznetsova et al. (2003); Mikhaylova et al. (2008)
LRR-1	CKI-1 (in C. elegans)	Starostina et al. (2010)
	p21Cip	Starostina et al. (2010)
FEM1B	TRA-1	Starostina et al. (2007)
	Ankrd37	Shi et al. (2011)