Table 2.

Cul5-type ubiquitin ligases and corresponding substrates.

Cul5-type ubiquitin ligases	Substrates	References
SOCS1	JAK2	Kamizono et al. (2001)
	Vav	De Sepulveda et al. (2000)
	IRS1 and IRS2	Rui et al. (2002)
ElonginA	Rpb1	Yasukawa et al. (2008)
SSB1, 2, and 4	iNOS	Kuang et al. (2010); Nishiya et al. (2011)
WSB1	HIPK2	Choi et al. (2005, 2008)
	D2	Dentice et al. (2005)
ASB2	Filamin A and B	Heuze et al. (2008)
	Jak3	Nie et al. (2011); Wu and Sun (2011)
ASB3	TNF-R2	Chung et al. (2005)
ASB4	IRS4	Li et al. (2011)
ASB6	APS	Wilcox et al. (2004)
ASB9	CKB	Debrincat et al. (2007)
ASB11	DeltaA (in Danio rerio)	Diks et al. (2006, 2008)