Figure 1.

Stimulatory effect of MEHP on basal steroidogenesis in immature granulosa cells (A) and Leydig cell progenitors (B). The cells were cultured without or with MEHP at different concentrations for 24 h. Testosterone (T) and 5α-androstane-3α-17β-diol (3α-Adiol) in the culture medium from Leydig cells and progesterone from granulosa cell cultures were then measured by RIA. The mean values ± SEM for four independent steroidogenic cell preparations are presented. *p < 0.05, **p < 0.01 compared to untreated control.