Table 5.
Overall statistical results of the F1 prognostic biomarker model with respect to both the discovery and the validation studies combined {identification of 93 subjects [20 responders (R) and 73 non-responders (NR)]}.
| Prognostic test | ROC AUC | Sensitivity | Specificity | T-value | P (2-tailed) α = 0.001 | R group Mean ± SD |
NR group Mean ± SD |
|---|---|---|---|---|---|---|---|
| Overall results (discovery and validation studies) | |||||||
| F1 | 0.9616 | 0.9000 | 0.9178 | 7.2454 | 1.36 × 10−10 | 4.4148 ± 0.2617 | 5.2921 ± 0.5223 |
Notes: The overall ROC AUC value, the overall sensitivity, the overall specificity, the T value and probability of significance (P) of the independent t-Test, and the mean score of the R group (Responders) and that of the NR group (Non-Responders), along with their respective standard deviations, of the F1 prognostic biomarker model with respect to both the discovery and the validation studies combined are shown.