Table 1.

Frequency of the A(133)S SNP in normal and breast cancer patient populations of Non-African American and African American women.

RASSF1A	Codonl33Ala/Ser Ser (S) = A Ala (A) = C	rs 2073498
African Americans	Cases (N = 742)	Controls (N = 658)
Allele frequencies	C = 0.98	C = 0.97
Chi-square P-value = 0.03	A = 0.02	A = 0.03
Genotype frequencies	C/C 713 (96%)	C/C 616 (94%)
Chi-square P-value = 0.08	C/A 29 (4%)	C/A 41 (6%)
	A/AO	A/A 1(0.1%)
Hardy Weinberg test P-value	0.59	0.71
Non-African Americans	Cases (N = 1230)	Controls (N = 1118)
Allele frequencies	C = 0.88	C = 0.88
Chi-square P-value =	A = 0.12	A = 0.12
Genotype frequencies	C/C 952 (77%)	C/C 875 (78%)
Chi-square P-value =	C/A 258 (21%)	C/A 223 (20%)
	A/A 20 (2%)	A/A 20 (2%)
Hardy Weinberg test P-value	0.60	0.19