Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Chemical vectors targeting the EGFR. The core structural elements of the chemical vectors targeting the EGFR consists of branched polyethyleneimine tethered by polyethyleneglycol to an EGFR homing ligand EGF or a peptide GE11. The tetraconjugate possesses a melittin moiety that facilitates endosomal release. The triconjugate is composed of a linear and shorter polyethyleneimine molecule tethered to the EGFR homing ligand via a short polyethyleneglycol.
