Table 3.

Early versus delayed radiation therapy/impact on progression-free and overall survival.

Author (year)	Patients	Early RT	RT at relapse
Sung et al. (1981)	10	–	70.9%, 10 years OS
Regine et al. (1993)	58	78%, 20 years OS	25%, 20 years OS
Stripp et al. (2004)	40	83%, 10 years OS	86%, 10 years OS
Tomita and Bowman (2005)	30	71%, 5 years PFS	90%, 5 years PFS
Moon et al. (2005)	50	91.3%, 10 years PFS	91.2%, 10 years PFS
Lin et al. (2008)	31	100%, 10 years LC	32%, 10 years LC

RT, radiotherapy; OS, overall survival; PFS, progression-free survival; LC, local tumor control.