Table 3.
Prevalence of single and multiple infections of individual HPV types among Chinese women with or without cervical lesions.
| HPV type | Total (n = 2374) | Normal cervix (n = 2199) | Cervix with low-grade lesions or worse (n = 175) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Prevalence of single infection (95% CIa) | Prevalence of multiple infections (95% CIa) | Prevalence ratiob | Prevalence of single infection (95% CIa) | Prevalence of multiple infections (95% CIa) | Prevalence ratiob | Prevalence of single infection (95% CIa) | Prevalence of multiple infections (95% CIa) | Prevalence ratiob | |
| ALPHA-9 SPECIES | |||||||||
| HPV16 (n = 87) | 2.27 (1.71–2.96) | 1.39 (0.96–1.95) | 0.61 | 1.32 (0.88–1.90) | 1.15 (0.73–1.72) | 0.87 | 19.4 (13.08–27.12) | 10.1 (4.95–17.79) | 0.52 |
| HPV31 (n = 25) | 0.59 (0.32–0.99) | 0.46 (0.23–0.83) | 0.79 | 0.52 (0.26–0.92) | 0.45 (0.21–0.85) | 0.87 | 2.24 (0.46–6.4) | 2.02 (0.25–7.11) | 0.90 |
| HPV33 (n = 17) | 0.34 (0.15–0.66) | 0.38 (0.17–0.72) | 1.13 | 0.23 (0.08–0.55) | 0.35 (0.14–0.72) | 1.52 | 2.24 (0.46–6.4) | 2.02 (0.25–7.11) | 0.90 |
| HPV35 (n = 6) | 0.13 (0.03–0.37) | 0.13 (0.03–0.37) | 1.00 | 0.09 (0.01–0.34) | 0.10 (0.01–0.36) | 1.11 | 0.75 (0.02–4.09) | 1.01 (0.03–5.5) | 1.35 |
| HPV52 (n = 46) | 1.10 (0.72–1.60) | 0.84 (0.52–1.30) | 0.77 | 0.89 (0.54–1.39) | 0.65 (0.35–1.11) | 0.73 | 5.22 (2.13–10.47) | 7.07 (2.89–14.03) | 1.35 |
| HPV58 (n = 50) | 1.01 (0.65–1.50) | 1.10 (0.72–1.60) | 1.08 | 0.66 (0.36–1.1) | 0.75 (0.42–1.23) | 1.14 | 7.46 (3.64–13.3) | 11.11 (5.68–19.01) | 1.49 |
| HVP67 (n = 8) | 0.08 (0.01–0.30) | 0.25 (0.09–0.55) | 3.00 | 0.09 (0.01–0.34) | 0.20 (0.05–0.51) | 2.22 | 0.00 (0.00–2.72) | 2.02 (0.25–7.11) | NAc |
| ALPHA-7 SPECIES | |||||||||
| HPV18 (n = 26) | 0.55 (0.45–1.20) | 0.55 (0.45–1.20) | 1.00 | 0.42 (0.19–0.8) | 0.30 (0.11–0.65) | 0.71 | 2.99 (0.82–7.47) | 7.07 (2.89–14.03) | 2.36 |
| HPV45 (n = 15) | 0.17 (0.05–0.43) | 0.46 (0.23–0.83) | 2.75 | 0.09 (0.01–0.34) | 0.35 (0.14–0.72) | 3.89 | 1.49 (0.18–5.29) | 4.04 (1.11–10.02) | 2.71 |
| HPV39 (n = 25) | 0.46 (0.23–0.83) | 0.59 (0.32–0.99) | 1.27 | 0.42 (0.19–0.8) | 0.45 (0.21–0.85) | 1.07 | 1.49 (0.18–5.29) | 5.05 (1.66–11.39) | 3.39 |
| HVP59 (n = 15) | 0.38 (0.17–0.72) | 0.25 (0.09–0.05) | 0.67 | 0.33 (0.13–0.68) | 0.10 (0.01–0.36) | 0.30 | 1.49 (0.18–5.29) | 4.04 (1.11–10.02) | 2.71 |
| HVP68 (n = 8) | 0.21 (0.07–0.49) | 0.13 (0.03–0.37) | 0.60 | 0.19 (0.05–0.48) | 0.05 (0.00–0.28) | 0.26 | 0.75 (0.02–4.09) | 2.02 (0.25–7.11) | 2.69 |
| OTHER SPECIES | |||||||||
| HPV6 (n = 5) | 0.17 (0.05–0.43) | 0.04 (0.00–0.23) | 0.25 | 0.19 (0.05–0.48) | 0.05 (0.00–0.28) | 0.26 | 0.00 (0.00–2.72) | 0.00 (0.00–3.66) | NA |
| HPV11 (n = 9) | 0.17 (0.05–0.43) | 0.21 (0.07–0.49) | 1.25 | 0.19 (0.05–0.48) | 0.15 (0.03–0.44) | 0.79 | 0.00 (0.00–2.72) | 2.02 (0.25–7.11) | NA |
a95% CI, 95% confidence interval; bprevalence ratio, prevalence of multiple infections/prevalence of single infection; cNA, not available.