Table 1.
Author | N | Schema | Results |
---|---|---|---|
Andersen (1978) | 108 | RT versus best supportive care | Post-op RT significantly improves survival compared to best supportive care |
Walker et al. (1978) | 303 | BCNU versus RT versus BCNU+RT versus best supportive care | Patients receiving RT had longer MS than patients receiving BCNU or best supportive care |
Walker et al. (1980) | 467 | Semustine versus RT versus semustine+RT versus BCNU+RT | Patients receiving RT had longer survival than patients receiving semustine alone |
Kristiansen et al. (1981) | 118 | RT versus RT+bleomycin versus best supportive care | Median survival with RT alone 10.2 versus 5.2 months with best supportive care |
Chang et al. (1983) | 538 | RT 60 Gy versus RT 70 Gy versus RT 60 Gy+BCNU versus RT 60 Gy+methyl-CCNU+dacarbazine | Dose escalation beyond 60 Gy or the addition of chemotherapy did not improve survival outcomes and BCNU did not improve overall or median survival |