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. 2011 Oct 28;1:36. doi: 10.3389/fonc.2011.00036

Table 1.

Role of radiotherapy in glioblastoma.

Author N Schema Results
Andersen (1978) 108 RT versus best supportive care Post-op RT significantly improves survival compared to best supportive care
Walker et al. (1978) 303 BCNU versus RT versus BCNU+RT versus best supportive care Patients receiving RT had longer MS than patients receiving BCNU or best supportive care
Walker et al. (1980) 467 Semustine versus RT versus semustine+RT versus BCNU+RT Patients receiving RT had longer survival than patients receiving semustine alone
Kristiansen et al. (1981) 118 RT versus RT+bleomycin versus best supportive care Median survival with RT alone 10.2 versus 5.2 months with best supportive care
Chang et al. (1983) 538 RT 60 Gy versus RT 70 Gy versus RT 60 Gy+BCNU versus RT 60 Gy+methyl-CCNU+dacarbazine Dose escalation beyond 60 Gy or the addition of chemotherapy did not improve survival outcomes and BCNU did not improve overall or median survival