Table A1.
Summary of individual studies involved in the current analysis.
| Study location (reference†) | Recruitment period | Platform/method¥ | Case subjects |
Control subjects‡ |
|||
|---|---|---|---|---|---|---|---|
| Source | Participation rate, % | Age eligibility years | Source | Participation rate, % | |||
| Europe | |||||||
| Paris, France (Benhamou et al., 2004) | 1987–1992 | PCR-RFLP | Hospital | 95§ | NA | Hospital (unhealthy) | 95§ |
| Central Europe (Banska Bystrica, Bucharest, Budapest, Lodz, Moscow)|| (Hashibe et al., 2006) | 1998–2003 | TaqMan | Hospital | 96 | ≥15 | Hospital (unhealthy) | 97 |
| Rome (Boccia et al., 2008) | 2002–2007 | PCR-RFLP | Hospital | 98 | NA | Hospital (unhealthy) | 94 |
| Western Europe (Canova et al., 2009) | 2000–2005 | APEX | Hospital | 82 | Hospital (unhealthy)* | 68 | |
| Heidelberg, Germany (Risch et al., 2003) | 1998–2000 | PCR-RFLP | Hospital | 96 | <80 | Population registry | 62 |
| North America | |||||||
| Seattle, WA Crump et al. (2000), Huang et al. (2005), Schwartz et al. (2001) | 1985–1995 | PCR-RFLP, multiplex, or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry | Cancer registry | 54.4, 63.3¶ | 18–65 | Random digit dialing | 63, 61¶ |
| Iowa (Wang et al., 2005) | 1993–2006 | PCR-RFLP | Hospital | 87 | >17 | Hospital (healthy) | 92 |
| North Carolina (Olshan et al., 2000) | 1994–1997 | Multiplex | Hospital | 88 | >17 | Hospital (unhealthy) | 86 |
| Los Angeles, CA (Cui et al., 2006) | 1999–2004 | PCR-RFLP | Cancer registry | 49 | 18–65 | Neighborhood | 67.5 |
| Houston, TX (Zhang et al., 2005) | 2001–2006 | PCR-RFLP | Hospital | 95 | ≥18 | Hospital visitors | >80 |
| Northeast, US (Park et al., 2003) | 1994–2000 | PCR-RFLP | Hospital | NA | Hospital (unhealthy) | ||
| Latin America | |||||||
| Puerto Rico (Hayes et al., 1999) | 1992–1995 | PCR-RFLP or TaqMan | Cancer registry | 71 | 21–79 | Residential records | 83 |
| Asia | |||||||
| India (Anantharaman et al., 2007) | 2001–2004 | PCR-RFLP | Hospital | NA | Hospital (unhealthy) | ||
| Japan (Suzuki et al., 2007) | 2001–2005 | TaqMan | Hospital | 61 | 20–79 | Hospital (unhealthy) | 41 |
NA = not applicable/not available.
†Representative publication in which study methods are described.
‡All studies frequency matched control subjects to case subjects on age and sex. Additional frequency matching factors included study center (Central Europe), hospital (France study), ethnicity (Northeast US), neighborhood (Los Angeles study), and tobacco and alcohol habits (India).
§Participation rate was not formally assessed, estimated response rate reported.
||Multicenter study.
¶Two response rates are reported because data were collected in two population-based case–control studies, the first from 1985 to 1989 among men and the second from 1990 to 1995 among men and women.
*The three UK centers (Glasgow, Manchester, and Newcastle) from the Western European study were chosen from the same family medical practice (population-based).