Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sunitinib down-regulates HSD3B2 expression at protein level. (A) HSD3B2 protein expression in NCI-H295 cells after 24 h of incubation with sunitinib was assessed by immunoblot analysis using a specific antibody. (B) Densitometric quantification of immunoblot signals from three experiments confirmed a significant sunitinib-induced decrease of HSD3B2 to 82 ± 8% (1 μM, n.s.), 63 ± 8%** (5 μM), and 54.6 ± 8.8%** (10 μM) compared to control cells (100 ± 6%). **p < 0.01 compared to control.
