TABLE 2.
Analysis of Variance Parent Behavioral Questionnaires (Mean t Score ± SD)
| XXY | XYY | Controls | P valuea | |
|---|---|---|---|---|
| CBCL-Problem behaviors | ||||
| n | 82 | 26 | 50 | |
| Behavior summary scores (Lower is better) | ||||
| Behavior total | 61.3 ± 12.0b | 67.3 ± 10.0c | 46.7 ± 10.0 | .0001a |
| Internalizing total | 59.3 ± 11.3b | 62.7 ± 12.0c | 46.0 ± 9.3 | .0001a |
| Externalizing total | 54.7 ± 12.7 | 61.3 ± 11.3c,d | 46.0 ± 11.3 | .0001a |
| Problem Behaviors | ||||
| Withdrawn | 58.7 ± 9.30b | 64.0 ± 11.3c,d | 51.3 ± 3.3 | .0001a |
| Somatic complaints | 61.3 ± 8.70b | 60.0 ± 9.30c | 54.7 ± 6.0 | .0001a |
| Anxious/depressed | 59.7 ± 9.30b | 62.7 ± 12.0c | 52.0 ± 4.7 | .0001a |
| Social problems | 64.7 ± 10.7b | 67.3 ± 11.3c | 52.0 ± 4.7 | .0001a |
| Thought problems | 58.7 ± 8.70b | 66.7 ± 10.7c,d | 52.0 ± 4.0 | .0001a |
| Attention problems | 64.0 ± 11.3b | 70.0 ± 10.0c,d | 52.7 ± 4.7 | .0001a |
| Delinquent behavior | 57.3 ± 8.0b | 60.0 ± 9.30c | 52.0 ± 3.3 | .0001a |
| Aggressive behavior | 58.0 ± 10.0b | 63.3 ± 10.7c,d | 53.3 ± 5.3 | .0001a |
| Sex problems | 56.7 ± 10.0b | 58.0 ± 12.0 | 52.0 ± 5.3 | .01a |
| CBCL Social competence scales (Higher is better) | ||||
| Activities total | 45.0 ± 7.30b | 43.0 ± 8.0c | 50.0 ± 6.0 | .0001a |
| Social total | 40.0 ± 10.0b | 37.0 ± 10.7c | 49.0 ± 6.0 | .0001a |
| School total | 33.0 ± 7.30b | 31.0 ± 6.7c | 50.0 ± 7.3 | .0001a |
| CPRS (Lower is better) | ||||
| Oppositional | 58.0 ± 12.0b | 66.0 ± 12.0c,d | 49.3 ± 8.7 | .0001a |
| Cognitive problems/Inattention | 62.0 ± 10.7b | 66.7 ± 10.0c | 47.3 ± 7.3 | .0001a |
| Hyperactivity | 57.3 ± 12.7 | 66.0 ± 12.7c,d | 52.7 ± 10 | .0001a |
| Anxiety-shy | 59.3 ± 12.0b | 62.7 ± 14.0c | 49.3 ± 8.0 | .0001a |
| Perfectionism | 52.7 ± 10.7b | 58.0 ± 12.7c | 47.3 ± 8.0 | .0001a |
| Social problems | 60.0 ± 14.0b | 69.3 ± 14.7c,d | 48.7 ± 8.0 | .0001a |
| Psychosomatic | 60.7 ± 14.7b | 58.0 ± 14.0c | 49.3 ± 8.7 | .003a |
| Global index: ADHD index | 61.3 ± 11.3b | 66.0 ± 9.3c | 48.0 ± 8.0 | .0001a |
| Global index: Restless/impulsive | 59.3 ± 11.3b | 66.0 ± 10.0c,d | 50.0 ± 9.3 | .0001a |
| Global index: Emotional lability | 61.3 ± 12.0b | 69.3 ± 12.7c,d | 47.3 ± 8.7 | .0001a |
| DSM-IV-Inattentive | 60.7 ± 10.7b | 66.0 ± 10.7c,d | 48.0 ± 8.0 | .0001a |
| DSM-IV Hyperactive-impulsive | 58.7 ± 12.7b | 66.0 ± 11.3c,d | 52.0 ± 10.0 | .0003a |
| DSM-IV total | 60.0 ± 11.3b | 66.7 ± 10.0c | 50.0 ± 8.7 | .0001a |
| SCQ (raw scores), (n) | 7.6 ± 6.3 (34) | 15.1 ± 9.9c,d (22) | 2.9 ± 2.4 (31) | .0001a |
| % > cutoff = 15 | 4/34 (12%) | 11/22 (50%) | 0/31 | .0001a |
a
ANOVA, comparison of 3 groups.
b
P < .05, XXY versus controls, ANOVA (post hoc).
c
P < .05, XYY versus controls, ANOVA (post hoc).
d
P < .05, XYY versus XXY, ANOVA (post hoc).