Table 4.

Effect of Amino Acid Addition on the Process-Associated Loss, Storage Stability, and Residual Water Content of F. tularensis Following Foam Drying. The formulation further comprised 30% (w/v) trehalose and 25 mM potassium phosphate at pH 8.0 (n = 2 replicates per data point or # of experiment, except for residual water content analysis, for which n = 3)

Amino Acid	Process Loss (log10 CFU ± s.d.)	Stability Loss, 1 Week at 37°C (log10 CFU ± s.d.)	Residual Water (%)
None	1.0 ± 0.2	3.1 ± 0.1	5.2 ± 0.1
Methionine, 0.5% (w/v)	0.6 ± 0.2	2.3 ± 0.3	4.2 ± 0.2
2% (w/v)	0.5 ± 0.2	3.5 ± 0.2	5.5 ± 0.4
Arginine, 0.5% (w/v)	0.3 ± 0.2	4.9 ± 0.1	3.8 ± 0.4
2% (w/v)	0.4 ± 0.2	ND	4.5 ± 0.8
4% (w/v)	0.6 ± 0.2	3.8 ± 0.9	4.1 ± 0.3