Table 5.

Effect of DMSO Addition on the Process-Associated Loss, Storage Stability, and Residual Water Content of F. tularensis Following Foam Drying. The formulation further contained 30% (w/v) trehalose and 25 mm potassium phosphate at pH 8.0 (n = 2 replicates per data point or # of experiment, except for residual water content analysis, for which n = 3).

DMSO	Process Loss (log10 CFU ± s.d.)	Stability Loss, 1 Week at 37°C (log10 CFU ± s.d.)	Residual Water (%)
None	1.0 ± 0.1	3.0 ± 0.1	5.2 ± 0.1
0.5 (wt %)	0.9 ± 0.1	2.7 ± 0.5	4.9 ± 0.3
2.4 (wt %)	0.9 ± 0.2	2.4 ± 0.6	4.7 ± 0.3