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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: J Pharm Sci. 2011 Apr 13;100(8):3076–3087. doi: 10.1002/jps.22563

Table 7.

Calculated Rate Constant of Degradation for the Five Formulations, Fr 3–Fr 7, at Three Storage Temperatures

Rate Constant of Degradation (log/week0.5 ± s.d.)
Formulation T = 37°C T = 25°C T = 4°C
Fr 3 −3.45 ± 0.02 ND ND
Fr 4 −0.93 ± 0.03 −0.33 ± 0.09 −0.11 ± 0.10
Fr 5 −1.07 ± 0.08 −0.56 ± 0.05 −0.25 ± 0.04
Fr 6 −0.87 ± 0.08 −0.33 ± 0.02 −0.04 ± 0.02
Fr 7 −0.91 ± 0.07 −0.27 ± 0.01 −0.01 ± 0.02

ND, Not determined.