Table 1.
Drug release characteristics of two drugs (dopamine and doxorubicin) from TNT/Ti wire showing their drug loading and release characteristics (% and mass) during burst and 8-days release period
| Drug loaded into TNT/Ti | Amount loaded drug | Cumulative drug release (% and μg) | Rate of drug release | ||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| 6 hours | 2 days | 4 days | 8 days | Burst release | After burst release | ||
| Dopamine | 170 μg | 60% | 70% | 80% | 100% | 17 μg/hour | 9 μg/day |
| 100 μg | 120 μg | 135 μg | 170 μg | ||||
| Doxorubicin | 1200 μg | 25% | 36% | 50% | 100% | 50 μg/hour | 112 μg/day |
| 300 μg | 435 μg | 620 μg | 1200 μg | ||||
Abbreviations: TNT, titania nanotube; Ti, titanium.