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Fluorescent images of Kupffer cells transfected with naked pEGFP (A), SLN/DNA (B), PEG-PE-SLN/DNA (C), A-MN-SLN/DNA (D), and B-MN-SLN/DNA (E) at 24, 48, and 72 hours after transfection.
Abbreviations: SLN, solid lipid nanoparticles; A-MN-SLNs/DNA, pre-MN-PEG-PE-modified SLN/DNA; B-MN-SLNs/DNA, post-MN-PEG-PE-modified SLN/DNA; MN, mannan; PEG, polyethylene glycol; PE, L-α-phosphatidylethanolamine; pEGFP, plasmid-enhanced green fluorescent protein.
