Table 4.
Summary of extracellular matrix-related gene expressions on Days 3, 6, and 9
| VEGFA | ITGB | ICAM1 | LAMA1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|||||||||
| D3 | D6 | D9 | D3 | D6 | D9 | D3 | D6 | D9 | D3 | D6 | D9 | |
| NT | + | + | + | + | + | + | / | / | / | + | +2 | / |
| NT-F-L | +2 | +2 | +2 | +3 | +2 | +2 | / | / | / | +2 | +3 | + |
| NT-F-M | +3 | +2 | +4 | +4 | +4 | +2 | + | + | + | +2 | +3 | + |
| NT-F-H | +4 | +3 | +3 | +2 | +3 | +2 | − | +2 | + | − | + | + |
Notes: +, Upregulated compared with PT (P < 0.01); −, downregulated (P < 0.01);/, no significant difference compared with PT.
Abbreviations: ICAM1, intercellular adhesion molecule 1; ITGB, β-integrin; LAMA1, laminin-1; NT, nanotube; PT, polished titanium; VEGFA, vascular endothelial growth factor A.