Table 4. According to different sexual or reproductive histories subgroup stratified analyses between the genotypes and CIN risk.
| High risk exposure | Controls(%) | CIN cases(%) | Adjusted OR**(95% CI) | P | ||
| TT* | TC or CC* | TT* | TC or CC* | |||
| Number of sexual partners | ||||||
| ≤1 | 204(31.8) | 438(68.2) | 123(32.3) | 258(67.7) | 0.98(0.75–1.28) | 0.866 |
| >1 | 53(33.5) | 105(66.5) | 25(25.3) | 74(74.7) | 1.49(0.85–2.62) | 0.161 |
| Age at the first intercourse | ||||||
| ≤20 years | 73(30.9) | 163(69.1) | 50(32.7) | 103(67.3) | 0.92(0.60–1.43) | 0.717 |
| >20 years | 184(32.6) | 380(67.4) | 98(30.0) | 229(70.0) | 1.13(0.84–1.52) | 0.412 |
| Number of parities | ||||||
| ≤3 | 118(32.7) | 243(67.3) | 63(33.9) | 123(66.1) | 0.95(0.65–1.38) | 0.781 |
| >3 | 139(31.7) | 300(68.3) | 84(28.7) | 209(71.3) | 1.15(0.83–1.59) | 0.389 |
| Age at the first parity | ||||||
| ≤22 years | 45(29.0) | 110(71.0) | 35(33.7) | 69(66.3) | 0.81(0.47–1.38) | 0.430 |
| >22 years | 212(32.9) | 433(67.1) | 112(29.9) | 262(70.1) | 1.15(0.87–1.51) | 0.335 |
| Oral contraceptive | ||||||
| Yes | 3(21.4) | 11(78.6) | 2(20.0) | 8(80.0) | 1.09(0.15–8.12) | 0.932 |
| No | 254(32.3) | 532(67.7) | 146(31.1) | 324(68.9) | 1.06(0.83–1.36) | 0.645 |
*
CC: PARP-1 Ala762Ala(GCG/GCG); TC: Val762Ala(GTG/GCG); TT: Val762Val(GTG/GTG).
**
all P-values adjusted for age.