Table 5. Analysis of association between the polymorphisms and risk of cervical carcinoma.
Genotypes* | Control(%),total = 800 | Carcinomas(%),total = 539 | adjusted OR**(95% CI) | P | Squamous cell carcinoma(%),total = 489 | adjusted OR**(95% CI) | P |
TT | 257(32.1) | 152(28.2) | 1.00 | 139(28.4) | 1.00 | ||
TC | 475(59.4) | 283(52.5) | 0.39(0.79–1.29) | 0.594 | 255(52.1) | 0.84(0.67–1.05) | 0.135 |
CC | 68(8.5) | 104(19.3) | 2.70(1.47–3.70) | <0.001 | 95 (19.5) | 2.56(1.47–3.70) | <0.001 |
TC or CC | 543(67.9) | 387(71.8) | 1.20(0.95–1.53) | 0.127 | 350(71.6) | 1.19(0.93–0.52) | 0.163 |
CC: PARP-1 Ala762Ala(GCG/GCG); TC: Val762Ala(GTG/GCG); TT: Val762Val(GTG/GTG).
all P-values adjusted for age.