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. 2012 May 18;7(5):e37244. doi: 10.1371/journal.pone.0037244

Figure 3. Dose-dependent inhibition of flavivirus replication by LCTA-949 and ribavirin.

Figure 3

Vero-B cell cultures infected with DENV-2 (panels A and B) or YFV-17D (panels C and D) were treated with different concentrations of LCTA-949 (panels A and C) or ribavirin (panels B and D). Viral RNA levels were quantified on day 4 p.i. by means of RNA RT-qPCR (bars). Mock-infected cells were treated with the same dilution series of LCTA-949 or ribavirin. Cell viability was determined by the MTS/PMS method (lines). Data represent mean values ± standard deviations (SD) for three independent experiments.